Lung Conditions Biography
(Source google.com)
Lung diseases can be congenital
or acquired after birth. Many lung diseases are life-threatening, or lead to
chronic morbidity (debility). Millions of people in the United States
and world-wide are affected by lung disease of one kind or another. Life-saving
surfactant therapy for respiratory distress syndrome (RDS), which occurs in
infants born prematurely, was developed at Cincinnati Children’s by Dr.
Whitsett. This therapy alone has resulted in a major reduction in perinatal
deaths in the United States
and countries world-wide. In a similar manner, groups in our division are
actively seeking new reatments and
therapies for many other lung diseases that affect children and adults. Using a
wealth of cutting-edge approaches (many of which have been developed in our
division) our groups work on the pathogenesis (causes) of lung diseases with
the goal of identifying new therapeutic targets. Some of the lung diseases
being studied in the Division of Pulmonary Biology include:
udicious use of antibiotics can
decrease adverse effects of antibiotics as well as decrease costs. But more
importantly, decreased antibiotic usage will prevent the rise of drug resistant
bacteria, which is now a growing problem in the world. Health authorities have
been strongly encouraging physicians to decrease the prescribing of antibiotics
to treat common upper respiratory tract infections because antibiotic usage
does not significantly reduce recovery time for these viral illnesses. Some
have advocated a delayed antibiotic approach to treating URIs which seeks to
reduce the consumption of antibiotics while attempting to maintain patient
satisfaction. Most studies show no difference in improvement of symptoms
between those treated with antibiotics right away and those with delayed
prescriptions. Most studies also show no difference in patient satisfaction,
patient complications, symptoms between delayed and no antibiotics. A strategy
of "no antibiotics" results in even less antibiotic use than a
strategy of "delayed antibiotics". However, in certain higher risk
patients with underlying lung disease, such as chronic obstructive pulmonary
disease (COPD), evidence does exist to support the treatment of bronchitis with
antibiotics to shorten the course of the illness and decrease treatment
failure. Chronic obstructive pulmonary
disease (COPD), which includes emphysema, is an example of an obstructive lung
disease where the alveolae rupture, thus causing air to be retained in the
lungs and hence limiting now a growing problem in the world. Health authorities have been strongly encouraging physicians to decrease the prescribing of antibiotics to treat common upper respiratory tract infections because antibiotic usage does not significantly reduce recovery time for these viral illnesses. Some have advocated a delayed antibiotic approach to treating URIs which seeks to reduce the consumption of antibiotics while attempting to maintain patient satisfaction. Most studies show no difference in improvement of symptoms between those treated with antibiotics right away and those with delayed prescriptions. Most studies also show no difference in patient satisfaction, patient complications, symptoms between delayed and no antibiotics. A strategy of "no antibiotics" results the available space during inhalation. Asthma is an example of an
obstructive lung disease (and of an inflammatory lung disease). It is a disease
in which muscles of bronchi contract, making it difficult for air to reach the
lungs. One treatment of asthma is to use an inhaler which contains a drug to
relax muscles of bronchi. Asthma is a difficulty in breathing causing wheezing
due to inflammation of bronchi and bronchioles, this causes a restriction in
the airflow into the alveoli. Asthma attacks can be brought on
by triggers, such as air pollution, tobacco smoke, factory fumes, cleaning
solvents, infections, pollens, dust, foods, cold air, exercise, chemicals and
medications. Triggers are highly individual and may not be related to
allergens. Many asthmatics are not allergic to common allergens such as mold.
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